Table 2 PC regression in cohort 1

From: Atrophy of ventral diencephalon is associated with freezing of gait in Parkinson’s disease: analysis of two cohorts

 

Model 1

Model 2

 

OR (95% CI)

P value

OR (95% CI)

P value

PC1

0.916 (0.733–1.145)

0.442

0.902 (0.699–1.164)

0.428

PC2

0.779 (0.621–0.977)

0.031

0.735 (0.568–0.951)

0.019

PC3

0.979 (0.784–1.224)

0.855

1.025 (0.796–1.320)

0.849

Age

1.029 (1.006–1.052)

0.014

1.018 (0.991–1.046)

0.187

Disease duration

1.006 (1.002–1.010)

0.006

0.998 (0.993–1.003)

0.502

Hoehn–Yahr stage

2.305 (1.702–3.121)

<0.001

1.490 (1.009–2.200)

0.045

MDS-UPDRS III

1.034 (1.020–1.048)

<0.001

1.023 (1.006–1.040)

0.009

Levodopa daily dosage

1.002 (1.001–1.003)

<0.001

1.002 (1.001–1.003)

0.003

MoCA

0.971 (0.935–1.009)

0.128

1.017 (0.975–1.061)

0.428

  1. Model 1 was unadjusted.
  2. Model 2 adjusted for age, disease duration, Hoehn–Yahr stage, MDS-UPDRS III, MoCA, and levodopa dosage. All parameters entered the models simultaneously.
  3. CI confidence interval, OR odds ratio, PC principal component, MDS-UPDRS III movement disorder society united Parkinson’s disease rating scale part III, MoCA Montreal cognitive assessment.
  4. Bold values identify statistical significance (P < 0.05).
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