Table 1 Demographic and clinical characteristics of study participants

From: Detecting neuropsychiatric fluctuations in Parkinson’s Disease using patients’ own words: the potential of large language models

Patients with PD

N = 33

Demographic characteristics

 

Sex assigned at birth (M/F)

24/9

Age (years), mean ± STD (min-max)

64.3 ± 7.7 (48–77)

Languages, n (%)

 - Swiss-German

21 (63.7%)

 - French

8 (24.2%)

 - Italian

4 (12.1%)

Disease duration (years) ± STD, (min-max)

10.3 ± 3.4 (3.0–18.0)

Clinical characteristics, mean ± STD (min-max)

MDS-UPDRS I

12.8 ± 5.8 (2.0–28.0)

MDS-UPDRS II

15.5 ± 6.8 (2.0–26.0)

MDS-UPDRS III: OFF medication

44.1 ± 12.0 (24.0–73.0)

MDS-UPDRS III: ON medication

19.7 ± 7.3 (7.0–38.0)

MDS-UPDRS IV

10.5 ± 3.9 (0.0–17.0)

Neuropsychiatric State Score: ON medication

48.2 ± 8.7 (26.0–60.0)

Neuropsychiatric State Score: OFF medication

17.2 ± 12.0 (0.0–49.0)

QUIP-RS

9.9 ± 11.3 (0.0–41.0)

SAS

10.5 ± 4.2 (3.0–19.0)

HADS -Anxiety

5.9 ± 3.9 (0.0–15.0)

HADS-Depression

4.2 ± 3.0 (0.0–16.0)

MoCA

25.9 ± 2.7 (20–30)

Average Speech Length (seconds)

44.8 ± 14.9 (15.2–106)

Speech length in ON medication

43.7 ± 11.8 (15.2-76.7)

Speech length in OFF medication

45.9 ± 17.6 (17.1-106)

  1. PD Parkinson’s disease, F female, M male, STD standard deviation, MDS-UPDRS Movement Disorder Society–Unified Parkinson’s Disease Rating Scale, QUIP-RS Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease Rating Scale, HADS Hospital Anxiety and Depression Scale, MoCA Montreal Cognitive Assessment.