Table 3 Correlation values of serum MPO concentration and activity with the characteristics of the study population
From: Association between serum myeloperoxidase enzyme activity and Parkinson’s disease status
Clinical parameter | MPO concentration | P value | MPO activity | P value |
|---|---|---|---|---|
Serum MPO concentration (pg/ml) | - | 0.306 | <0.0001 | |
Serum MPO activity (U/L) | 0.306 | <0.0001 | - | |
Age (years) | 0.057 | NS | −0.045 | NS |
Aging (middle-age, elderly) | 0.009 | NS | −0.059 | NS |
Sex (men, women) | 0.016 | NS | −0.128 | NS |
Body mass index (kg/m2) | −0.025 | NS | −0.025 | NS |
Education (years) | −0.081 | NS | −0.081 | NS |
PD status (yes, no) | 0.344 | <0.0001 | 0.453 | <0.0001 |
Hypertension (yes, no) | −0.007 | NS | −0.016 | NS |
Dysthyroidism (yes, no) | −0.049 | NS | 0.251 | <0.0001 |
Type 2 diabetes mellitus (yes, no) | 0.021 | NS | −0.108 | NS |
Dyslipidemia (yes, no) | −0.132 | NS | −0.198 | 0.005 |
Coronary artery disease (yes, no) | −0.026 | NS | −0.193 | 0.004 |
Stroke (yes, no) | 0.116 | NS | −0.035 | NS |
Depressive disorder (yes, no) | 0.031 | NS | 0.205 | 0.004 |
Anxiety (yes, no) | 0.112 | NS | 0.108 | NS |
Hypertension treated with ACEIs (yes, no) | 0.087 | NS | −0.023 | NS |
Hypertension treated with diuretics (yes, no) | −0.102 | NS | 0.058 | NS |
Hypertension treated with calcium antagonists (yes, no) | −0.006 | NS | 0.009 | NS |
Use of β-blockers (yes, no) | 0.101 | NS | 0.083 | NS |
Antithyroid drug therapy (yes, no) | 0.098 | NS | 0.014 | NS |
Levothyroxine therapy (yes, no) | −0.049 | NS | 0.265 | <0.0001 |
Insulin use (yes, no) | −0.035 | NS | 0.103 | NS |
Type 2 diabetes treated with metformin, (yes, no) | 0.018 | NS | −0.099 | NS |
Type 2 diabetes treated with combination of metformin and aGLP-1 (yes, no) | 0.001 | NS | −0.010 | NS |
Dyslipidemia with lifestyle and dietary modifications (yes, no) | −0.045 | NS | 0.101 | NS |
Statins use (yes, no) | −0.137 | NS | −0.378 | <0.0001 |
NSAIDs use (yes, no) | −0.055 | NS | −0.175 | 0.006 |
Use of SSRI antidepressants (yes, no) | 0.094 | NS | 0.159 | 0.025 |
Use of non-SSRI antidepressants (yes, no) | 0.021 | NS | 0.141 | 0.046 |
Benzodiazepine therapy (yes, no) | 0.033 | NS | 0.131 | NS |
LEDD (mg) | 0.374 | <0.0001 | 0.290 | <0.0001 |
