Table 4 Stepwise, backward/forward, multivariate logistic regression analysis with adjustments for MPO parameter and covariates, and PD status as dependent factor

From: Association between serum myeloperoxidase enzyme activity and Parkinson’s disease status

     

95% CI for Exp(B)

Model 1. MPO concentration

B

SE

Wald

P value

Exp(B)

lowest

highest

Backward & forward

Intercept

−2.954

0.584

25.603

0.000

0.052

  

Serum MPO concentration

0.000

0.000

4.433

0.035

1.000

1.000

1.001

Sex (male)

1.097

0.547

4.017

0.051

2.994

1.024

8.751

LEDD

0.174

7.767

0.001

0.982

1.190

0.000

 

Model 2. MPO activity

B

SE

Wald

P value

Exp(B)

lowest

highest

Backward & forward

Intercept

−7.513

2.238

11.295

0.001

0.001

  

Serum MPO activity

1.936

0.568

11.604

0.001

6.921

2.274

21.065

Depression (yes)

−2.108

0.682

9.567

0.002

0.121

0.032

0.462

LEDD

0.179

8.361

0.000

0.983

1.195

0.000

 
  1. The model 1 includes PD status as dependent factor, and serum MPO concentration (continuous), “age” (continuous), “sex”, “hypertension”, “dysthyroidism”, “type 2 diabetes mellitus” (all categorical), and “LEDD” (continuous) as covariates. R2 = 0.597 (Cox and Snell).
  2. The model 2 includes PD status as dependent factor, and serum MPO activity (continuous), “age” (continuous), “sex”, “hypertension”, “dysthyroidism”, “type 2 diabetes mellitus” (all categorical), as well as “LEDD” (continuous), “depression”, “CAD,” “statins use,” and “NSAIDs use” (all categorical) as covariates. R2 = 0.624 (Cox and Snell). Factors associated with PD status are indicated in cursive. LEDD levodopa equivalent daily dose, MPO myeloperoxidase, P probability, PD Parkinson’s disease.
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