Table 1 Clinical data and imaging findings of the subjects
NC | PD | p | PD-RBD | PD-nRBD | p | |
|---|---|---|---|---|---|---|
(n = 33) | (n = 91) | (n = 55) | (n = 36) | |||
Age (years) | 62.6 ± 6.1 | 65.2 ± 8.0 | 0.062 | 65.4 ± 7.0 | 64.9 ± 9.2 | 0.076 |
Sex (M/F) | 17/16 | 39/52 | 0.392 | 23/32 | 16/20 | 0.804 |
MMSE | 27.79 ± 2.26 | 27.98 ± 2.13 | 0.667 | 28.02 ± 1.79 | 27.92 ± 2.60 | 0.826 |
EDU (years) | 10.30 ± 3.29 | 12.80 ± 3.15 | <0.001* | 12.85 ± 3.12 | 12.72 ± 3.24 | 0.846 |
LED | NA | 459.87 ± 275.72 | NA | 493.46 ± 270.76 | 408.55 ± 241.54 | 0.131 |
Dur (years) | NA | 7.65 ± 4.19 | NA | 7.67 ± 3.88 | 7.61 ± 4.69 | 0.946 |
UPDRS-I | NA | 3.04 ± 2.16 | NA | 3.42 ± 1.90 | 2.47 ± 2.41 | 0.040* |
UPDRS-II | NA | 12.51 ± 5.49 | NA | 13.40 ± 5.64 | 11.14 ± 5.01 | 0.054 |
UPDRS-III | NA | 30.77 ± 11.93 | NA | 32.04 ± 12.52 | 28.83 ± 10.85 | 0.212 |
UPDRS-IV | NA | 2.36 ± 2.38 | NA | 2.62 ± 2.64 | 1.97 ± 1.89 | 0.177 |
UPDRS-total | NA | 49.52 ± 17.73 | NA | 52.36 ± 18.26 | 45.17 ± 16.18 | 0.058 |
HY | NA | 2.5 (2–3) | NA | 2 (2–3) | 2.5 (1.5–3) | 0.507 |
HAMD | NA | 9.90 ± 6.11 | NA | 11.2 ± 6.0 | 7.9 ± 5.9 | 0.011* |
HAMA | NA | 10.96 ± 6.67 | NA | 11.8 ± 6.5 | 9.6 ± 6.8 | 0.120 |
SSQ | NA | 1 (0–1) | NA | 1 (1–2) | 0 (0–0) | <0.001* |
Imaging findings | ||||||
ALPS-index | 1.53 ± 0.17 | 1.42 ± 0.16 | 0.002* | 1.39 ± 0.15 | 1.47 ± 0.17 | 0.017* |
BG-EPVS | 1 (1–1) | 1 (1–1) | 0.585 | 1 (1–1) | 1 (1–1) | 0.953 |
CSO-EPVS | 0 (0–1) | 0 (0–1) | 0.088 | 0 (0–1) | 0 (0–1) | 0.254 |
