Table 2 Changes in ‘OFF’ time measured with the Hauser diary according to study group

From: Parkinson’s disease medication adjustments based on wearable device information compared to other methods: randomized clinical trial

 

Visit Group n = 55

Diary Group n = 51

Sensor Group n = 50

Regression analysis

Comparison

Estimate

CI

p-value

Percentage OFF time, Mean (SD)

Baseline

29.3 (12.2)

26.9 (13.3)

31.7 (14.0)

DG vs. VGa

−5.91

−12.63 to 0.82

0.085

Final

29.1 (19.3)

23.4 (15.2)

29.4 (17.4)

SG vs. VGa

−1.36

−8.03 to 5.32

0.689

p-value (Baseline vs. Final)

0.962

0.227

0.4707

 
  1. CI confidence interval, DG Diary Group, SD standard deviation, SG Sensor Group, VG Visit Group.
  2. aObservations = 148, R2/R2 adjusted=0.181/0.146, AIC = 1259.514.
  3. Model adjusted by equivalent dopaminergic dose, UPRS-II, UPDRS-III, and ‘OFF time’ at baseline.