Fig. 4: Correlations between DTI-ALPS indices, functional connectivity, and depression severity.

A Scatter plot showing a negative correlation between the left DTI-ALPS index and HAMD scores. B Positive correlation between seed-based FC values in the right ITG and HAMD scores. C Negative association between the left DTI-ALPS index and FC values in the right mPFC. DTI-ALPS diffusion tensor imaging analysis along the perivascular space, HAMD Hamilton Depression Scale, FC functional connectivity, ITG inferior temporal gyrus, mPFC medial prefrontal cortex.