Table 1 Demographic characteristics and clinical measurements of the included participants

From: Investigating glymphatic function and bed nucleus of the stria terminalis-based functional connectivity in Parkinson’s disease with and without depression

Variables

Patients

HC (n = 25)

F/Z value

P value

PDD (n = 24)

PDND (n = 24)

Age

66.46 ± 8.19

64.50 ± 9.93

62.28 ± 6.88

3.24

0.198a

Education

11.71 ± 3.44

13.42 ± 2.64

12.32 ± 2.82

3.31

0.190a

Gender (M/F)

14/10

11/13

11/14

1.18

0.554b

HAMA*

10.71 ± 3.99

6.58 ± 3.22

3.00 ± 4.04

34.74

0.000a

HAMD*

16.08 ± 5.33

4.92 ± 1.91

4.04 ± 1.97

44.98

0.000a

MADRS*

12.46 ± 5.90

4.88 ± 3.27

2.84 ± 4.29

37.78

0.000a

BDI*

8.63 ± 3.44

3.58 ± 2.19

2.32 ± 3.42

37.29

0.000a

UPDRS total*

70.79 ± 26.83

47.71 ± 21.04

NA

−3.02

0.003c

UPDRS I*

11.08 ± 3.84

6.67 ± 3.14

NA

−3.62

0.000c

UPDRS II*

13.88 ± 6.26

8.71 ± 5.81

NA

−2.89

0.004c

UPDRS III*

42.92 ± 17.92

30.92 ± 13.53

NA

−2.47

0.014c

UPDRS IV

2.92 ± 3.79

1.42 ± 2.30

NA

−1.00

0.316c

H&Y stage*

2.33 ± 0.67

1.89 ± 0.64

NA

−2.23

0.026c

MMSE

28.38 ± 1.81

28.88 ± 1.23

28.24 ± 1.39

2.38

0.305a

  1. M male, F female, HAMA Hamilton Anxiety Scale, HAMD Hamilton Depression Scale, MADRS Montgomery-Asberg Depression Rating Scale, BDI Beck’s Depression Inventory, UPDRS unified Parkinson’s disease rating scale, H&Y stage Hoehn & Yahr stage, NA not applicable, PD Parkinson’s disease, PDD PD patients with depression, PDND PD patients with non-depression, HC healthy control, MMSE Mini-Mental State Examination.
  2. ap values were obtained by Kruskal–Wallis test.
  3. bp value for the gender difference was obtained by chi-square test.
  4. cp values were obtained by Mann–Whitney U test.
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