Fig. 5: Correlations between PRS, plasma biomarkers and gray matter volume. | npj Parkinson's Disease

Fig. 5: Correlations between PRS, plasma biomarkers and gray matter volume.

From: Genetic risk and plasma biomarkers of dementia with Lewy bodies in a Chinese population

Fig. 5

A PRS and p-tau217; B PRS and GFAP; C PRS and αSyn; D PRS and NfL; E the voxel-based gray matter volume and plasma NfL levels in DLB patients. The yellow area in the plot represents the area negatively correlated with plasma NfL levels, mainly concentrated in the bilateral temporal lobes. PRS polygenic risk score, P-tau phosphorylated tau, NfL neurofilament light chain, GFAP glial fibrillary acidic protein, αSyn α-synuclein, DLB dementia with Lewy bodies.

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