Fig. 3: The distribution of Gradient 3 and its relationships with functional networks.

A The distribution of the striatum functional atlas, created using a custom winner-take-all parcellation method. B The global histogram of Gradient 3 showed that the extreme values at both ends in all PD subgroups were suppressed compared to HC. C The distributions of the gradient scores within the striatum for each subgroup mapped to the Yeo-7 network parcellation. HC healthy controls, PD-NC normal cognitive, PD-MCI mild cognitive impairment, PDD Parkinson’s disease dementia, VN visual network, DAN dorsal attention network, VAN ventral attention network, FPN frontoparietal network, DMN default mode network.