Fig. 6: SNCA expression stratified by demographic, clinical, and biological factors. | npj Parkinson's Disease

Fig. 6: SNCA expression stratified by demographic, clinical, and biological factors.

From: Decreased SNCA expression in whole-blood RNA analysis of Parkinson’s disease adjusting for neutrophils

Fig. 6

a–c Gene counts were log(CPM) normalized and corrected for predicted neutrophil percentage. a SNCA expression in samples stratified by genetic status and diagnosis. The dotted red line represents the median SNCA expression in HC samples (i.e., ‘Control’ and ‘SNCA−/GBA1−/LRRK2−’). b SNCA expression of HC, IPD, PD-SNCA+ samples, PD-GBA1+ samples, and PD-LRRK2+ samples at baseline only. c SNCA expression of IPD samples over age at baseline. All p values were calculated using a Wilcoxon rank-sum test. *, **, *** indicate p values less than 0.05, 0.01. and 0.001, while N.S. indicates no significance.

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