Table 1 Top 20 significantly upregulated differentially expressed genes in G2019S-infected neutrophils compared to WT-infected

From: Lrrk2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis

Genes

p_val

avg_log2FC

pct.1

pct.2

p_val_adj

Plaur

4.2896E-17

2.56646846

0.722

0.466

8.9249E-13

Irf1

3.224E-13

2.9665498

0.79

0.561

6.7079E-09

Actg1

1.9157E-10

17.3159898

0.982

0.951

3.9858E-06

Fgl2

8.2326E-10

9.70633498

0.757

0.587

1.7129E-05

Tap1

1.5713E-09

1.59248386

0.572

0.323

3.2693E-05

Irgm1

1.6212E-09

5.40865353

0.489

0.256

3.3731E-05

Cxcl10

2.6077E-09

60.5959953

0.491

0.269

5.4256E-05

Samhd1

1.4522E-08

11.5421141

0.888

0.776

0.00030215

Rhoh

6.3858E-08

2.65791361

0.402

0.202

0.00132863

Ccl6

2.1192E-07

14.5666966

0.683

0.48

0.00440919

Gbp7

2.6187E-07

3.02910595

0.527

0.318

0.00544852

Gbp5

4.5256E-07

15.8374442

0.593

0.408

0.00941592

Rnasel

5.4518E-07

8.45985251

0.375

0.188

0.01134309

Ccr1

6.2266E-07

3.79811961

0.86

0.74

0.01295515

Nampt

6.7531E-07

2.56407938

0.579

0.381

0.01405041

Snx20

7.6411E-07

6.43647727

0.902

0.865

0.01589812

Srgn

9.5358E-07

40.3982648

0.998

1

0.01984016

H2-D1

1.0444E-06

3.58743132

0.985

0.951

0.02173024

Gdap10

1.3744E-06

2.6104548

0.36

0.184

0.02859656

Ifi47

1.5055E-06

7.95125562

0.428

0.238

0.03132359

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