Fig. 1: Transmission electron microscopy of sonicated α-syn mPFFs reveals that the high-power sonicator produces much shorter PFFs than the conventional sonicator. | npj Parkinson's Disease

Fig. 1: Transmission electron microscopy of sonicated α-syn mPFFs reveals that the high-power sonicator produces much shorter PFFs than the conventional sonicator.

From: Impact of α-synuclein fibril structure on seeding activity in experimental models of Parkinson’s disease

Fig. 1

A–F α-syn mPFFs after 1 min (S1), 5 min (S5), 30 min (S30), 60 min (S60), or 120 min (S120) of sonication under strong conditions of a high-power sonicator, or after 5 min of sonication (W5) under weak conditions. G mPFFs after 5 min of sonication in a conventional bath sonicator (C5). H Unsonicated mPFFs. A–G Histograms and median PFF lengths are shown below the electron microscope images. Scale bars: 100 nm.

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