Fig. 2: Knockdown of enzymes in the polyamine pathway alters longevity in the α-Syn Drosophila model. | npj Parkinson's Disease

Fig. 2: Knockdown of enzymes in the polyamine pathway alters longevity in the α-Syn Drosophila model.

From: Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinson’s Disease

Fig. 2

A Schematic of the polyamine pathway and the associated enzymes. B–Q Longevity analysis of neuronal knockdown of individual polyamine pathway enzymes in the α-Syn Drosophila model. B–I Show lifespan data for female flies, while panels (J–Q) present data for male flies. Statistical significance was determined using log-rank tests: ns (not significant), *(p < 0.05), **(p < 0.01), ***(p < 0.001), ****(p < 0.0001).

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