Table 1 The genotype of files used in each figure

From: Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinson’s Disease

Gene

Fly gene identifier

Fly stock number

Genotype

Phenotype when expressed in neuron

Used in figures

PA anabolic enzymes

 UAS-ODC1RNAi

CG8721

VDRC 30038

w1118; P{GD15056}v30038

Normal adults

Figs. 2–5

 UAS-ODC1RNAi

CG8721

VDRC 30039

w1118; P{GD15056}v30039/TM3

Normal adults

Data not included. An extra line for confirming the results.

 UAS-SRMRNAi

CG8327

VDRC 35883

w1118; P{GD13894}v35883

Normal adults

Figs. 2–5

 UAS-SRMRNAi

CG8327

BDSC 56011

y1 sc*v1 sev21; P{TRiP.HMC04307}attP40

Normal adults

Not in figures. An extra line for confirming the results.

 UAS-SMSRNAi

CG4300

VDRC 26500

w1118; P{GD11280}v26500

Normal adults

Figs. 2–5

 UAS-SMSRNAi

CG4300

BDSC 52924

y1 sc*v1 sev21; P{TRiP.HMC03665}attP40

Normal adults

Not in figures. An extra line for confirming the results.

PA catabolic enzymes

 UAS-SMOXRNAi

CG7737

BDSC 36904

y1 sc*v1 sev21; P{TRiP.GL01104}attP2

Normal adults

Figs. 2–5

 UAS-SMOXRNAi

CG7737

VDRC 49437

w1118; P{GD9951}v49437

Normal adults

Not in figures. An extra line for confirming the results.

 UAS-SAT1RNAi

CG4210

VDRC 104004

w1118; P{KK107727}VIE-260B

Normal adults

Figs. 2–5

 UAS-SAT1RNAi

CG4210

BDSC 50615

y1 v1; P{TRiP.HMC02982}attP2/TM3, Sb1

Normal adults

Not in figures. An extra line for confirming the results.

 UAS-PAOXRNAi

CG8032

VDRC 108652

w1118; P{KK100284}VIE-260B

Adults have developmental issues, such as unexpanded wings, and premature death.

Figs. 2–5

 UAS-PAOXRNAi

CG8032

BDSC 66967

y1 sc*v1 sev21; P{TRiP.HMS05433}attP40

Adults have developmental issues, such as unexpanded wings, and premature death.

Not in figures. An extra line for confirming the results.

PA transporters

 UAS-Anne (ATP13A2)RNAi

CG32000

VDRC 105477

w1118; P{KK107621}VIE-260B

Adults have developmental issues, such as unexpanded wings, and premature death.

Figs. 2–5

 UAS-Anne (ATP13A2)RNAi

CG32000

VDRC 29174

w1118; P{GD14627}v29174/TM3

Adults have developmental issues, such as unexpanded wings, and premature death.

Not in figures. An extra line for confirming the results.

 UAS-SLC7A2RNAi

CG7255

VDRC 107802

w1118; P{KK110010}VIE-260B

Adults have developmental issues, such as unexpanded wings, and premature death.

Figs. 2–5

Others

 UAS-α-Syn

Human gene

BDSC 51374

w1118; P{w[+mC]=UAS-SNCA.J}4

Normal adults

Figs. 1–6

 UAS-α-Syn

Human gene

BDSC 95240

w1118; P{w[+mC]=UAS-Hsap\SNCA.T}LP2

Normal adults

Not in figures. An extra line for confirming the results.

 elav-Gal4

Gal4

BDSC 458

w1118; P{GawB}elav[C155]

Unable to apply

Figs. 1–3, 5, 6

 sqh-Gal4

Gal4

Gift from Dr. Daniel Kiehart

w1118; sqh-Gal4; +

Unable to apply

Fig. 1

 GMR-Gal4

Gal4

BDSC8605

w1118; +; GMR-Gal4

Unable to apply

Fig. 4

 UAS-CD8GFP

Membrane-GFP

BDSC 5130

w1118; +;P{w+mC=UAS-mCD8::GFP.L}LL6

Normal adults

Fig. 4

 UAS-Ctrl

-

Gift from Jamie Roebuck (Duke U)

y, w; +; attP2 landing site

Normal adults

Figs. 1 and 6

 UAS-CtrlRNAi

-

VDRC 60000

w1118

Normal adults

Figs. 2–5

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