Fig. 4: Correlation of LID scores, L-DOPA levels and dopamine levels with plasmalogen PCs and PUFA-containing glycerophospholipids in specific brain regions.

a Schematic of a coronal non-human primate brain tissue section at −4 mm from the ac depicting different brain regions, with those evaluated labelled in red. b Results of Pearson’s correlation analysis between plasmalogen PC levels in the GPi, GPe, Put, Cd, Cl and PrG, and LID scores of the animals or levels of L-DOPA and dopamine obtained from the same regions of consecutive tissue sections. c Schematic of a coronal non-human primate brain tissue section at −4 mm from the ac depicting different regions, with those evaluated labelled in red. d Results of Pearson’s correlation analysis between glycerophospholipid levels in the GPi and GPe, and LID scores of the animals, as well as levels of L-DOPA and dopamine obtained from the same regions in consecutive tissue sections. Heat maps are colour-coded according to Pearson’s correlation coefficients: orange and blue colours indicate positive and negative correlations, respectively. Asterisks indicate significant correlations: *P < 0.05; **P < 0.01.