Fig. 6: Distribution of α-syn seeding activity across distinct neuroanatomical brain regions in PD and MSA cases using the α-syn-isSID assay.

Representative images illustrate the seeding activity assessed in multiple brain regions, including the medulla, pons, midbrain (SN), cerebellum, amygdala, cingulate cortex, entorhinal cortex, and the hippocampus using α-syn-isSID assay in PD (a) and MSA cases (b). Scale bar is 100 µm.