Fig. 4: Effects of CAP and Nic intervention on dopaminergic neurons in MPTP-induced mice. | npj Parkinson's Disease

Fig. 4: Effects of CAP and Nic intervention on dopaminergic neurons in MPTP-induced mice.

From: Capsaicin and nicotine alleviate MPTP induced olfactory dysfunction by suppressing cGAS/TBK1/STING and MAPK mediated neuroinflammation

Fig. 4

a Representative pictures displaying staining of TH in the olfactory bulb, olfactory tubercle regions, striatum and substantia nigra; b The average optical density of TH in the olfactory bulb region; c The average optical density of TH in the olfactory tubercle region. d The average optical density of TH in the striatum region; e The average optical density of TH in the substantia nigra region. Scale bar for the olfactory bulb = 200 μm; olfactory tubercle = 150 μm. striatum = 25 μm; substantia nigra = 100 μm. (n = 6 mice per group for a–e). Statistical analyses were performed by one-way ANOVA followed by Tukey’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

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