Fig. 5: Effects of CAP and Nic on microglia in the olfactory bulb of MPTP-induced mice. | npj Parkinson's Disease

Fig. 5: Effects of CAP and Nic on microglia in the olfactory bulb of MPTP-induced mice.

From: Capsaicin and nicotine alleviate MPTP induced olfactory dysfunction by suppressing cGAS/TBK1/STING and MAPK mediated neuroinflammation

Fig. 5

a Representative immunofluorescence images of Iba1 and CD68 in the glomerular layer of the olfactory bulb; b Representative immunofluorescence images of Iba1 and CD68 in the external plexiform layer of the olfactory bulb; c Ibar positive cells in the glomerular layer; d Iba1 and CD68 co-localization in the glomerular layer; e Iba1 endpoints in the glomerular layer; f Iba1 process length in the glomerular layer; g Ibar positive cells in the external plexiform layer; h Iba1 and CD68 co-localization in the external plexiform layer; i Iba1 endpoints in the external plexiform layer; j Iba1 process length in the external plexiform layer. Iba1: green; CD68: red; DAPI: blue; Images were captured using a 63× objective, scale bar = 25 μm; enlarge scale bar = 2.5 μm. (n = 6 mice per group for a–j). Statistical analyses were performed by one-way ANOVA followed by Tukey’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001.

Back to article page