Table 2 Accuracy of each symptom (A) for detecting OAD and (B) for detecting asthma in patients who have OAD
Symptom | Sensitivity, % | Specificity, % | Positive predictive value, % | Negative predictive value, % |
|---|---|---|---|---|
A Accuracy for detecting OAD | ||||
Breathlessness (mMRC grade ≥ 1) | 97.30 | 75.61 | 93.51 | 88.57 |
Breathlessness > 6 months | 94.59 | 78.05 | 93.96 | 80.00 |
Cough | 93.24 | 78.05 | 93.88 | 76.19 |
Cough > 6 months | 89.86 | 82.93 | 95.00 | 69.39 |
Cough with expectoration | 42.57 | 85.37 | 91.30 | 29.17 |
Wheeze | 83.11 | 92.68 | 97.62 | 60.32 |
B Accuracy for detecting asthma in patients who have OAD | ||||
Wheeze | 89.57 | 39.39 | 83.74 | 52.00 |
Intermittent asymptomatic period | 92.17 | 87.88 | 96.36 | 76.32 |
Smoker | 85.22 | 75.76 | 92.45 | 59.52 |
Pack years < 10 years | 90.43 | 75.76 | 92.86 | 69.44 |
Family history of atopy | 53.91 | 78.79 | 89.86 | 32.91 |
Current age < 40 years | 28.70 | 90.91 | 91.67 | 26.79 |
Age of onset of breathlessness < 40 years | 66.09 | 87.88 | 95.00 | 42.65 |
Age of onset of cough < 40 years | 68.70 | 87.88 | 95.18 | 44.62 |
