Table 4 Multivariable analysis of the sub-group of patients with PEF data available describing risk predictors for at least one asthma attack defined by the American Thoracic Society criteria

From: Applying UK real-world primary care data to predict asthma attacks in 3776 well-characterised children: a retrospective cohort study

Reference category

Comparison

Odds ratio (95% CI)

p Value

Overall p value

Blood eosinophil count

    

≤400/µL

>400/µL

1.48 (1.15, 1.91)

<0.001

0.002

GINA management step

    

0

1/2

1.04 (0.67, 1.61)

0.867

<0.001

3

1.65 (1.00, 2.73)

0.050

4/5

2.53 (1.43, 4.46)

0.001

GP consults for LRTIs

    

0

1+

1.48 (1.02, 2.14)

0.040

0.003

Asthma attack

    

0

1

3.72 (2.73, 5.06)

<0.001

<0.001

2+

7.81 (5.18, 11.76)

<0.001

% predicted PEF

    

Per 1% increase

0.995 (0.990, 1.000)

0.036

0.036

Age

   

Per year of age

0.92 (0.87, 0.97)

0.004

0.004

  1. The results are from a multivariable analysis. The following variables were significantly associated with asthma attack in the univariate analyses but were not significant in the multivariate model: hayfever diagnosis ever, eczema diagnosis ever, overall asthma control, daily short-acting β-agonist dosage and average inhaled corticosteroid daily dose.
  2. GINA Global INitiative for Asthma, LRTI Lower respiratory tract infection
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