Table 3 Evidence summary to support practice resources and organisation.

From: Improving primary care management of asthma: do we know what really works?

Practice resources and organisation

Country(Reference)

Study type

Description and study outcomes

Registered pt lists and fully integrated computer systems AND Clinical care pathways

UK22

Questionnaire; no data

SIMPLES, a structured PC approach to reviewing pts with uncontrolled asthma—encompassing pt education monitoring, lifestyle/pharmacological management and addressing support needs. Involves close cooperation between PC and SC. Outcomes: No data available.

Registered pt lists and fully integrated computer systems AND Clinical care pathways

NL23

Questionnaire; no data

SIMPLES adapted using a modified e-Delphi approach to assess the stakeholder opinion. Outcomes: Nine-component questionnaire—a robust and holistic approach for difficult-to-manage asthma. No data available.

Registered pt lists and fully integrated computer systems

UK24

Cluster-randomised trial in 29 PC practices with 911 at-risk asthma pts

Pilot study showed that PC intervention for targeted at-risk asthma patients had the potential for improving practice level management and reducing asthma emergency admissions.

Registered pt lists and fully integrated computer systems

UK25

Pragmatic, 2-arm, RCT; 270 PC practices covering >10,000 registered ‘at-risk asthma’ pts

Aimed to determine whether the creation and integration of at-risk asthma registers into PC reduces asthma-related crisis events for at-risk pts over a 12-month period compared to control practices. Outcomes: No data available.

Registered pt lists and fully integrated computer systems

UK26

Retrospective study; 26 at-risk asthma pts and 26 matched controls for 1 year pre- and post-intervention

Implementation/service use costs estimated before and 1 year after introduction of an at-risk register. More ‘at-risk’ than control pts were hospitalised/attended A&E/nebulised for asthma; also used out-of-hours services/attended GP/received OCS (all p < 0.025). Outcomes: After register introduction, no at-risk pts were admitted or attended A&E.

Registered pt lists and fully integrated computer systems

Multi-national (US, NL, AU, UK, DK)27

Systematic review of 19 studies representing 16 RCTs (2003–2013) evaluating CCDS for pts with asthma and COPD

Use of CCDS improved asthma and COPD care in 14 of the reviewed studies (74%). There was considerable improvement in healthcare process measures and clinical outcomes. The effect on workload, efficiency, safety, costs, provider and pt satisfaction remain understudied.

Registered pt lists and fully integrated computer systems

Multi-national (US, NL, UK, ES)28

Systematic review of 8 RCT CCDS (1990–2012) for professional asthma management

Use of CCDS by HCPs was found to be low, and adherence to the advice was limited. Concluded, if used, CDSS could result in closer adherence to guidelines and improve some clinical outcomes. Better alignment to clinical workflow would enhance their use.

Registered pt lists and fully integrated computer systems

NL29

1-year RCT; 200 adults (18–50 years) with mild–moderate persistent asthma

Pt groups: (i) weekly asthma control monitoring via online ACQ, treatment adjusted via self-management algorithm supervised by an asthma nurse specialist; (ii) usual care. Outcomes: Weekly self-monitoring/treatment adjustment led to improved asthma control in pts with partly/uncontrolled asthma at baseline.

Access to high-quality lung function testing and other diagnostic tests

Unknown at present30

Protocol: This will be a systematic review

Clinical prediction models can be used to aid PC asthma diagnosis by estimating outcome; models combine ≥2 predictors, e.g. clinical history/physical examination/test results/treatment response. Outcomes: No data available.

Access to high-quality lung function testing and other diagnostic tests

NL31

Observational study

An online support system to advise GPs on pt diagnosis and treatment. Spirometry performed by local GP laboratory; spirometry results, pt history questionnaire, ACQ and CCQ reviewed online by pulmonologist; who advises GP online, supported by a guideline-based algorithm. Outcomes: Number of pts with unstable asthma (ACQ ≥ 1.5) dropped from 245 to 137.

Access to high-quality lung function testing and other diagnostic tests

NL32

PC Diagnostic Centre study. 156 pts randomly selected from asthma/COPD-service referrals

Five respiratory specialists assessed spirometry data and pt histories. Facilities developed to provide spirometry testing by specially trained clinicians. GPs reluctant to perform or interpret spirometry themselves may be supported diagnostically by respiratory specialists in an asthma service although the reliability of this advice varies.

Access to high-quality lung function testing and other diagnostic tests

UK33

PC study; 678 pts aged 4–80 years with first FeNO assessment at index date

FeNO use to guide ICS initiation/dosing decisions and identify poor adherence. In the year following index date, FeNO use was evaluated in 2 pt cohorts to: (i) identify steroid-responsive disease; (ii) guide asthma management. Outcomes: Algorithms to guide practical FeNO use could improve diagnostic accuracy/asthma regimen tailoring.

Access literacy/culturally sensitive pt education

 

No studies found via search

 
  1. ACQ Asthma Control Questionnaire, A&E Accident and Emergency department, AU Australia, CCQ Common Cold Questionnaire, CDDSS Computerised Clinical Decision Systems, COPD chronic pbstructive pulmonary disease, DK Denmark, ES Spain, FeNO Exhaled Nitric Oxide Test, GP General Practitioner, HCP healthcare practitioner, ICS inhaled corticosteroid, NL Netherlands, PC primary care, PTS patients, RCT randomised clinical trial, SC secondary care, UK United Kingdom, US United States.