Table 1 Asthma control in medium- and high-dose ICS/LABA cohort and reasons for uncontrolled asthma control.
Medium-dose ICS/LABA cohort (N = 24,937) | High-dose ICS/LABA cohort (N = 8661) | |
---|---|---|
Patients with uncontrolled asthma | 5707 (22.9%) | 1793 (20.7%) |
Reasons for uncontrolled asthma | ||
Episode of exacerbation | ||
Moderate exacerbation | 1455 (5.8%) | 676 (7.8%) |
Severe exacerbation | 197 (0.8%) | 92 (1.1%) |
Treatment step up | ||
ICS increased dose | 442 (1.8%) | 0 |
Addition of LAMA | 10 (0.0%a) | 11 (0.1%) |
Addition of LTRA | 1920 (7.7%) | 495 (5.7%) |
Addition of theophylline | 594 (2.4%) | 212 (2.5%) |
Maintenance systemic corticosteroids | 75 (0.3%) | 31 (0.4%) |
Addition of more than one asthma controller, including LTRA | 198 (0.8%) | 55 (0.6%) |
Addition of more than one asthma controller, excluding LTRA | 23 (0.1%) | 0 |
High-dose SABA | 568 (2.3%) | 186 (2.2%) |
Use of adrenaline | 633 (2.5%) | 169 (2.0%) |