Table 1 Demographics and clinical characteristics 12 months prior to and 12 months following MITT initiation.

From: Characteristics and treatment patterns of patients with asthma on multiple-inhaler triple therapy in Spain

 

12 months prior to MITT (pre-index) (N = 1204)

12 months following MITT (post-index) (N = 1204)

Demographics

Female, n (%)

851 (70.7)

 

Age at asthma diagnosis, mean (SD)

45.2 (15.9)

 

Age at MITT initiation, mean (SD)

54.8 (13.8)

 

Years from diagnosis to MITT, mean (SD)

9.6 (8.9)

 

Urban location, n (%)

1,023 (85.0)

 

Smoking status, n (%)

Non-smokera

708 (58.8)

717 (59.6)

Smoker

208 (17.3)

199 (16.5)

Former smoker

247 (20.5)

272 (22.6)

Unknown

41 (3.4)

16 (1.3)

BMIb

n = 640

n = 536

BMI, mean (SD) kg/m2

30.3 (6.2)

30.9 (6.3)

Spirometryc, mean (SD)

n = 387

n = 281

FEV1 % predicted value

70.8 (19.1)

75.4 (19.6)

FEV1/FVC ratio

70.1 (13.1)

73.6 (13.3)

Common comorbidities, n (%)

Anxiety/depression

459 (38.1)

 

Pneumonia

57 (4.7)

 

Other respiratory infections

373 (31)

 

Rhinitis

232 (19.3)

 

Hypertension

409 (34.0)

 

Diabetes mellitus

139 (11.5)

 

Gastroesophageal reflux

112 (9.3)

 

Conjunctivitis

12 (10.0)

 

Polyposis

76 (6.3)

 

Severe exacerbationsd; n (%)

667 (55.4)

503 (41.8)

Blood eosinophils (%), mean (SD)

n = 732

4.1 (3.4)

n = 717

4.1 (3.1)

  1. BMI body mass index, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, SD standard deviation, MITT multiple-inhaler triple therapy.
  2. aThe number of non-smokers is higher following MITT initiation as the smoking status for some patients only became available during that period;
  3. breported for patients with a BMI record in their medical history;
  4. creported for patients with spirometry measurements in their medical history;
  5. da severe exacerbation was defined as the need for one hospitalization or emergency visit or the use of oral/systemic corticosteroids (or increase in the maintenance dose) for at least 3 days due to asthma.