Table 2 Baseline characteristics of the Ext-SLS cohort and SLS ITT populations, as recorded at the time of entry into the SLS.
From: Extending the data collection from a clinical trial: The Extended Salford Lung Study research cohort
Asthma | COPD | |||
|---|---|---|---|---|
Ext-SLS population (N = 798) | SLS ITT population (N = 4233) | Ext-SLS population (N = 349) | SLS ITT population (N = 2799) | |
Sex, n (%) | ||||
Female | 515 (64.5) | 2498 (59.0) | 173 (49.6) | 1369 (48.9) |
Male | 283 (35.5) | 1735 (41.0) | 176 (50.4) | 1430 (51.1) |
Age, years | ||||
Mean (SD) | 53.4 (14.8) | 49.8 (16.4) | 65.4 (8.8) | 66.7 (9.9) |
Range | 18–88 | 18–91 | 41–91 | 40–93 |
Age group, n (%) | ||||
18 to 50 years | 318 (39.8) | 2151 (50.8) | 242 (69.3) | 1693 (60.5) |
>50 years | 480 (60.2) | 2082 (49.2) | 107 (30.7) | 1106 (39.5) |
Body Mass Index (BMI), kg/m2 | ||||
N with BMI available | 790 | 4152 | 311 | 2231 |
Mean (SD) | 29.9 (6.9) | 29.9 (6.9) | 28.1 (6.2) | 27.8 (6.5) |
Range | 17–70 | 15–70 | 16–50 | 12–77 |
Smoking status, n (%) | ||||
Current smoker | 109 (13.7) | 849 (20.1) | 146 (41.8) | 1289 (46.1) |
Ex-smoker | 261 (32.7) | 1366 (32.3) | 184 (52.7) | 1375 (49.1) |
Never smoker | 427 (53.5) | 1988 (47.0) | 19 (5.4) | 135 (4.8) |
Medical conditions at baseline | ||||
Any condition, n (%) | 335 (42.0) | 1625 (38.4) | 262 (75.1) | 2145 (76.6) |
Cardiovascular risk factors, n (%) | 214 (26.8) | 1094 (25.8) | 188 (53.9) | 1448 (51.7) |
Hypercholesterolemia | 180 (22.6) | 917 (21.7) | 181 (51.9) | 1298 (46.4) |
Diabetes mellitus | 68 (8.5) | 406 (9.6) | 36 (10.3) | 438 (15.6) |
Vascular disorders, n (%) | 236 (29.6) | 1099 (26.0) | 170 (48.7) | 1363 (48.7) |
Hypertension | 236 (29.6) | 1098 (25.9) | 169 (48.4) | 1355 (48.4) |
Cerebrovascular accident | 4 (<1) | 18 (<1) | 2 (<1) | 27 (<1) |
Cardiac disorders, n (%) | 56 (7.0) | 346 (8.2) | 67 (19.2) | 720 (25.7) |
Coronary artery disease | 27 (3.4) | 221 (5.2) | 50 (14.3) | 555 (19.8) |
Arrhythmia | 30 (3.8) | 144 (3.4) | 18 (5.2) | 239 (8.5) |
Congestive heart failure | 5 (<1) | 47 (1.1) | 13 (3.7) | 164 (5.9) |
Myocardial infarction | 3 (<1) | 8 (<1) | NR | 7 (<1) |
Asthma, n (%) | – | – | 69 (19.8) | 609 (21.8) |
