Table 3 Asthma disease characteristics in the Ext-SLS cohort and SLS ITT populations, captured at entry to the SLS.

From: Extending the data collection from a clinical trial: The Extended Salford Lung Study research cohort

 

Ext-SLS Population (N = 798)

SLS ITT Population (N = 4233)

Duration of asthma, n (%)a

<6 months

10 (1.3)

54 (1.3)

≥6 months to <1 year

11 (1.4)

77 (1.8)

≥1 to <5 years

82 (10.3)

438 (10.3)

≥5 to <10 years

97 (12.2)

519 (12.3)

≥10 years

598 (74.9)

3144 (74.3)

Any daytime symptoms more than twice a week?, n (%)

Yes

708 (88.7)

3830 (90.5)

No

90 (11.3)

403 (9.5)

Use of SABA more than twice a week?, n (%)

Yes

551 (69.0)

3044 (71.9)

No

247 (31.0)

1189 (28.1)

Any limitations of activities in the past week?, n (%)

Yes

385 (48.2)

2162 (51.1)

No

413 (51.8)

2071 (48.9)

Any nocturnal symptoms/awakening in past week?, n (%)

Yes

393 (49.2)

2117 (50.0)

No

405 (50.8)

2116 (50.0)

Total number of exacerbations (any severity) in the year prior to randomization, n (%)

0

513 (64.3)

2692 (63.6)

1

183 (22.9)

973 (23.0)

≥2

102 (12.8)

568 (13.4)

Mean (SD)

0.6 (1.2)

0.6 (1.1)

Range

0–12

0–14

Number of severe asthma exacerbations in year prior to randomization, n (%)

0

513 (64.3)

2692 (63.6)

≥1

285 (35.7)

1541 (36.4)

ACT score, n (%)

≥20

263 (33.0)

1210 (28.6)

16–19

250 (31.3)

1307 (30.9)

≤15

285 (35.7)

1716 (40.5)

Asthma symptoms, n (%)

<2 questions answered yes

141 (17.7)

634 (15.0)

≥2 questions answered yes

657 (82.3)

3599 (85.0)

  1. ACT Asthma Control Test, Ext-SLS Extended Salford Lung Study, ICS inhaled corticosteroid, ITT intention to treat, SABA short-acting β2-agonist, SD standard deviation, SLS Salford Lung Study.
  2. an = 4232.