Fig. 3 | npj Regenerative Medicine

Fig. 3

From: Biomaterials-enabled cornea regeneration in patients at high risk for rejection of donor tissue transplantation

Fig. 3

Regenerated patient corneas. a In vivo confocal images of the regenerated cornea from Patient 1 at 24 months post-operation, showing the regenerated epithelium, regenerating nerve (arrowhead) and stroma. The unoperated endothelium remains intact. b Changes in corneal touch sensitivity before and after RHCIII-MPC implantation as measured by Cochet-Bonnet aesthesiometry. The average pressure required to elicit a blink response from corneas before surgery, after implantation, and in comparison to the normal, healthy corneas. Touch sensitivity is inversely related to the pressure needed to elicit a blink response from the patients. Note: *p < 0.05 compared to unoperated contralateral eyes (Kruskal–Wallis test with Dunn’s correction for multiple comparisons)

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