Fig. 2

Release kinetics of free DFO and HA-DFO conjugates. In vitro testing of the three compounds in PBS at 37 °C (n = 3, Mean ± SD is shown). Note the rapid clearance of free DFO (t_1/2~0.5 h) in comparison to the sustained release patterns exhibited by both HA-DFO conjugates (t_1/2~10 d)