Fig. 6: Genomic profiling of p53 peaks after IFI16 knockdown during trilineage specification.
From: IFI16 promotes human embryonic stem cell trilineage specification through interaction with p53
a Histogram of p53 peak number after IFI16 knockdown during trilineage specification. b The distribution ratio of p53 peaks after IFI16 knockdown during trilineage specification. c, d Venn diagrams (c) and heatmaps (d) of genes enriched by p53 peaks after IFI16 knockdown during trilineage specification. e–g Biological processes gene ontology (GO) analysis for genes enriched by p53-shNC special peaks in differentiated trilineage (e, endoderm; f, mesoderm; g, ectoderm). Each node represented a specific GO term, and the node size indicated the number of genes in the GO term. The GO term annotations are listed in the Supplementary Dataset 1. ENDO, endoderm; MESO, mesoderm; ECTO, ectoderm.
