Fig. 1: Targets identified from exercised hearts protect against cardiac disorder via multiple avenues: killing multiple birds with one stone. | npj Regenerative Medicine

Fig. 1: Targets identified from exercised hearts protect against cardiac disorder via multiple avenues: killing multiple birds with one stone.

From: Targets identified from exercised heart: killing multiple birds with one stone

Fig. 1

Specific target identified from exercised heart (IGF1-PI3K/AKT signaling, C/EBP-β-CITED4, cardiac miRNAs (miR-222, miR-17-3p, etc.), exosomal-miRNAs (miR-342, miR-29, etc.), SIRT1 and Nrf2-Mts) was ‘stone’, multiple effects of exercise on hearts were ‘birds’. Therefore, exercise protects hearts via ‘killing multiple birds with one stone’.

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