Fig. 1: Analysis of changes in macrophage polarity produced by AD-MSC-sEVs (sEVs) or AD-MSC-γ-sEVs (γ-sEVs). | npj Regenerative Medicine

Fig. 1: Analysis of changes in macrophage polarity produced by AD-MSC-sEVs (sEVs) or AD-MSC-γ-sEVs (γ-sEVs).

From: Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis

Fig. 1

Forty-eight hours after the addition of vehicle (PBS), sEVs, and γ-sEVs, macrophages were harvested and the mRNA expression levels of genes encoding pro- (Il-6, Tnf-a, Mcp-1, Inos) and anti- (Il-10, Ym-1, Fizz-1, Cd206) inflammatory factors were evaluated using real-time PCR. Data are presented as means ± SD; n = 5 per experiment.

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