Table 1 Neocartilage regional biochemical content.

From: Engineering large, anatomically shaped osteochondral constructs with robust interfacial shear properties

Group

Region

Hydration [%]

GAG/WW [%]

GAG/DW [%]

GAG/DNA [μg/μg]

Col/WW [%]

Col/DW [%]

Col/DNA [μg/μg]

Early OC Assembly

Outer

85.6 ± 2.0

1.7 ± 0.4

11.4 ± 1.5

80.4 ± 13.2

1.0 ± 0.1

7.2 ± 0.8

8.0 ± 1.4

Inner

86.3 ± 0.6

1.3 ± 0.3

9.8 ± 1.7

75.0 ± 12.7

0.9 ± 0.1

6.5 ± 0.6

7.5 ± 1.4

Late OC Assembly

Outer

86.7 ± 1.2

1.5 ± 0.8

10.6 ± 5.7

114.9 ± 25.6a

1.1 ± 0.2a

8.4 ± 1.2a

11.5 ± 2.6a

Inner

87.8 ± 1.0

0.9 ± 0.2

8.2 ± 2.2

82.1 ± 12.1b

0.8 ± 0.1b

6.8 ± 0.4b

8.2 ± 1.2b

  1. Biochemical content was compared by region of neocartilage within each OC Assembly group. Paired t-tests comparing the inner vs. outer regions within the Early and Late OC Assembly groups were performed.
  2. GAG glycosaminoglycans, Col collagen, WW wet weight, DW dry weight, OC osteochondral.
  3. Data are presented as means ± standard deviations. Groups marked by different letters (i.e., a and b) are statistically different.
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