Fig. 3: Complex interplay between internal regulatory processes and the influence of local environmental cues. | npj Regenerative Medicine

Fig. 3: Complex interplay between internal regulatory processes and the influence of local environmental cues.

From: Induced pluripotency in the context of stem cell expansion bioprocess development, optimization, and manufacturing: a roadmap to the clinic

Fig. 3

Orchestration of phenotype is complex, depicted above in a conceptual interaction network. These interactions are illustrated to visualize the interplay between fundamental cellular processes. Ideal process control must be optimized to maintain strict homeostasis of the embryonic niche in pluripotent cell expansion bioprocessing by guiding cell network activity.

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