Fig. 5: Macrophage migration in an organoid/macrophage co-culture model.
From: Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium
A Immunofluorescence imaging demonstrating migration of CD68+ macrophages cultured from control (MΦcon) and SmoKO (MΦSmoKO) mice towards mouse gastric organoids. Co-cultures were treated with vehicle or gastrin. B Macrophage migration within the co-cultures was quantified by forward migration index (FMI). *P < 0.001 compared to vehicle, n = 6 individual co-culture experiments. Data are shown as the mean ± SEM.
