Table 1 Subcutaneous injection of AAT in healthy volunteers.

From: An immunologically active, adipose-derived extracellular matrix biomaterial for soft tissue reconstruction: concept to clinical trial

Subject

Age range

Sex

AAT implant time in situ

Excision

timepoint

Surgical procedure

Injection volumes (sites)

Total dose

01

60–69 y

M

29 d

4 wk

Panniculectomy

1 cc (2)

2 cc

02a

30–39 y

F

12 d

2 wk

Panniculectomy

1 cc (2)

2 cc

03

50–59 y

F

5 d

1 wk

Abdominoplasty

2 cc (1)

2 cc

04

20–29 y

F

16 d

2 wk

Abdominoplasty

1 cc (2)

2 cc

05

50–59 y

F

26 d

4 wk

Panniculectomy

1 cc (2)

2 cc

06

50–59 y

F

6 d

1 wk

Panniculectomy

1 cc (2)

2 cc

07

40–49 y

F

127 d

18 wk

Abdominoplasty

2 cc (1)

2 cc

08

60–69 y

F

39 d

6 wk

Panniculectomy

1 cc (2), 2 cc (1)

4 cc

Mean

48 y

 

32.5 d

   

2.25 cc

SD

13.6 y

 

40.0 d

   

0.71 cc

  1. aSubject 02 withdrew from the study prior to completing follow-up visits.