Fig. 2: Systemic and local administration of MBV prevents adverse bone remodeling in chronic pristane-induced arthritis by microCT imaging. | npj Regenerative Medicine

Fig. 2: Systemic and local administration of MBV prevents adverse bone remodeling in chronic pristane-induced arthritis by microCT imaging.

From: Immunomodulatory matrix-bound nanovesicles mitigate acute and chronic pristane-induced rheumatoid arthritis

Fig. 2

a Representative microCT images of forepaws at day 100. Substantial bone remodeling and damage are seen in the pristane + PBS group throughout the proximal bones of the forepaw while all three treatment groups show minimal to absent changes in bone morphology. Scale bar = 10 mm. b Representative microCT images of hind paws at day 100. Substantial bone remodeling and damage is seen in the pristane + PBS group localized to the tibiotalar joint while all three treatment groups show minimal to absent changes in bone morphology, especially in the region of the tibiotalar joint. Scale bar = 10 mm. Both panels a. and b. include both anterior–posterior (AP) and lateral views.

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