Fig. 2: PTCs proliferation and tubular expression of VEGF-A are induced after I/R injury. | npj Regenerative Medicine

Fig. 2: PTCs proliferation and tubular expression of VEGF-A are induced after I/R injury.

From: Tubular epithelial cells-derived small extracellular vesicle-VEGF-A promotes peritubular capillary repair in ischemic kidney injury

Fig. 2

a Western blotting analysis of PCNA in kidneys (n = 6). b Representative images of CD31- and PCNA-stained kidney sections. Scale bars, 100 μm (n = 6). c Quantification of PCNA+CD31+ cells (white arrowheads) on the basis of six mice, with at least 10 fields counted in each. d and e Representative confocal images of VEGF-A-stained kidney sections. Scale bars, 20 μm. Quantification on the basis of six mice, with at least ten sections counted in each. Zoom panels show the redistribution of VEGF-A from the cytoplasm to the basolateral side of TECs. Data are presented as means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs. Sham group. One-way ANOVA.

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