Fig. 4: Treatment of PTβR2I-releasing wound dressings stimulated angiogenesis and angiogenic growth factor secretion in diabetic wounds. | npj Regenerative Medicine

Fig. 4: Treatment of PTβR2I-releasing wound dressings stimulated angiogenesis and angiogenic growth factor secretion in diabetic wounds.

From: Thermosensitive and antioxidant wound dressings capable of adaptively regulating TGFβ pathways promote diabetic wound healing

Fig. 4

a Representative days 8 and 14 immunofluorescence stain images of vessel formation, made using CD31 and α-SMA (nuclei in blue using DAPI). Scale bar = 50 μm. b Relative CD31+ and α-SMA+ vessel density that is normalized to that of the No treatment group at day 8 (n = 5). The vessel density was quantified based on the images first followed by normalization. c The image of dots obtained from the angiogenesis protein array was performed using the tissue samples collected on day 8 post-treatment. d Band intensities of proteins in the angiogenesis array. All data demonstrated as mean ± standard deviation. Data were analyzed by one-way ANOVA with Bonferroni post-test **p < 0.01, ***p < 0.001).

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