Fig. 6: AAV9-cBIN1 rescues gross heart anatomy in minipigs with non-ischemic HFrEF. | npj Regenerative Medicine

Fig. 6: AAV9-cBIN1 rescues gross heart anatomy in minipigs with non-ischemic HFrEF.

From: Cardiac bridging integrator 1 gene therapy rescues chronic non-ischemic heart failure in minipigs

Fig. 6

a Frontal and transverse view of gross morphology of the minipig heart at termination. Scale bar, 5 cm. b Quantification of heart weight normalized to body weight. c Quantification of left ventricular (LV) cross area from transverse view (N = 3, 5, 4 from sham, control, and cBIN1 groups). Data are presented as mean ± standard error of the mean (SEM). Ordinary one-way ANOVA followed by uncorrected Fisher’s LSD test is used for comparison among three groups. *** indicates p < 0.001 for comparison vs. Sham. ## indicates p < 0.01 for comparison vs. Control.

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