Fig. 4: HA-Col click gels decreased scar formation associated with myofibroblastic activity in rat corneal stroma. | npj Regenerative Medicine

Fig. 4: HA-Col click gels decreased scar formation associated with myofibroblastic activity in rat corneal stroma.

From: Bio-orthogonal crosslinking and hyaluronan facilitate transparent healing after treatment of deep corneal injuries with in situ-forming hydrogels

Fig. 4

a Representative F-actin staining images of rat corneas on day 60. Quantification of (b) stromal F-actin intensities and (c) cell density in the wounded corneal stroma on day 60. d Representative α-smooth muscle actin (αSMA) staining in the stroma of rat corneas on day 60. e Quantification of αSMA intensities in the stroma on day 60. All data present mean ± SEM (n = 3 per group). Ordinary one-way ANOVA analysis was used to calculate the p values. *p < 0.05, **p < 0.01. HA is hyaluronic acid. Col is collagen. PBS is phosphate buffer solution. Graphs were created in GraphPad Prism 10.

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