Fig. 7: Single-cell proteomic analysis discriminates PG and SMG cells. | npj Regenerative Medicine

Fig. 7: Single-cell proteomic analysis discriminates PG and SMG cells.

From: Establishment of salivary tissue-organoid biorepository: characterizing salivary gland stem/progenitor cells and novel differentiation marker PSMA/FOLH1

Fig. 7

A Partial least squares discriminant analysis (PLS-DA) plot separates PG and SMG cells into distinct clusters. Proteins identified ≥50% of each cell types were used for the analysis after batch effect correction. Each circle represents data from an individual single cell. B Variable importance in projection (VIP) score plot of top 15 proteins discriminating PG and SMG cells. C Heatmap showing the hierarchical clustering of PG and SMG cells based on their protein expression. Red color represents up-regulated and blue color represents down-regulated. The differentially expressed proteins are mentioned on the y-axis, and PG and SMG cells on the x-axis. MetaboAnalyst (https://www.metaboanalyst.ca/docs/About.xhtml) was used to generated PLS-DA plot, VIP score plot and heatmap.

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