Fig. 6: FGF9-treated organoids present a more complex phenotype.
From: FGF9 treatment reduces off-target chondrocytes from iPSC-derived kidney organoids
A–D Immunostaining of cryosections showed an increase of the vasopressin-induced water channel aquaporin 2 (AQP2) in FGF9-treated organoids. Nuclei are stained with DAPI. Scale bars represent 100 µm. The off-target cell population (asterisks) observed in day 7 + 25 untreated organoids was not observed with FGF9 treatment. E–H BSA uptake assay revealed a higher staining (red) in FGF9-treated organoids compared to control at day 7 + 25. Nephrons (NPHS1) and proximal tubules (LTL) are present in both conditions. Nuclei were stained with DAPI. Scale bars represent 50 µm.
