Table 1 Significantly differentially methylated positions between t(1;11) carriers and non-carriers

Probe ID	Hg19 coordinates	Gene	Beta difference	Fold-change	t	p-value	q-value
cg09186051	Chr1:231981906	DISC1;TSNAX-DISC1	−0.07	−1.31	−11.81	1.17 × 10⁻¹³	5.20 × 10⁻⁸
cg26728851	Chr11:76430375	GUCY2E	−0.03	−1.63	−9.72	2.09 × 10⁻¹¹	4.64 × 10⁻⁶
cg15157974	Chr1:232144702	DISC1;TSNAX-DISC1	−0.04	−1.27	−9.04	1.30 × 10⁻¹⁰	1.92 × 10⁻⁵
cg05656812	Chr1:232021560	DISC1;TSNAX-DISC1	−0.06	−1.33	−8.44	6.73 × 10⁻¹⁰	7.46 × 10⁻⁵
cg06928246	Chr1:227974645	NA	−0.07	−1.56	−7.99	2.41 × 10⁻⁰⁹	0.0002
cg16177633	Chr1:232172585	DISC1;TSNAX-DISC1	−0.03	−1.20	−7.23	2.13 × 10⁻⁰⁸	0.0016
cg18815120	Chr1:231512676	EGLN1	−0.12	−2.10	−6.99	4.29 × 10⁻⁰⁸	0.003
cg25899154	Chr11:72897143	NA	−0.07	−1.28	−6.75	8.73 × 10⁻⁰⁸	0.005
cg02771260	Chr11:59836817	MS4A3	−0.13	−1.79	−6.66	1.13 × 10⁻⁰⁷	0.006
cg24508974	Chr10:103330391	NA	0.01	1.17	6.61	1.32 × 10⁻⁰⁷	0.006
cg21875980	Chr1:231553510	EGLN1	0.06	1.40	6.54	1.64 × 10⁻⁰⁷	0.007
cg26355502	Chr1:221916303	DUSP10	−0.01	−1.30	−6.24	4.05 × 10⁻⁰⁷	0.01
cg00965168	Chr1:227974541	NA	−0.05	−1.42	−6.10	6.03 × 10⁻⁰⁷	0.02

Table summarises significantly differentially methylated sites between t(1;11) carriers and non-carriers (FDR q ≤ 0.05). In order of column appearance are probe identifiers, Hg19 genomic coordinates, UCSC reference gene names (“NA” denotes intergenic regions), between-group difference in mean beta value, fold-change between groups, moderated t-statistic, p-value for differential methylation and FDR-adjusted p-value (q-value)

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