Table 1 Demographic and clinical data (mean and standard deviation) for neurotypical controls (NC), first-degree relatives (FDR), and participants with (SZ + FTD) and without (SZ−FTD) formal thought disorder
NC (n = 15) | FDR (n = 15) | SZ + FTD (n = 15) | SZ−FTD (n = 15) | F(df)Pa (n = 15) | |
---|---|---|---|---|---|
Mean age (years) | 45 (13.0) | 45 (13.0) | 50 (14.6) | 38 (7.3) | 2.4 (3,56) 0.080 |
Sex #male | 7 | 8 | 13 | 10 | |
Years of education | 16 (3.6) | 17 (4.1) | 15 (3.6) | 13 (4.0) | 3.0 (3,56) 0.038 |
NART | 109 (8.7) | 101 (12.2) | 96 (14.2) | 95 (14.0) | 4.1(3,55) 0.010 |
IQ* | 107 (8.5) | 103 (9.9) | 80 (15.7) | 87 (19.9) | 12.0(3,56) < 0.0005 |
Illness duration (months) | None | 30 (80.4) | 232 (149.3) | 199 (88.6) | |
PANSS item 2 | 1(0) | 1.3(0.6) | 5.2(0.9) | 1.5(0.6) | |
PANSS positive subscale | 8.2(0.9) | 12 (5.9) | 30 (5.0) | 21 (4.6) | |
PANSS negative subscale | 9 (1.4) | 12 (6.1) | 27 (7.7) | 20 (6.8) | |
PANSS General Psychopathology Subscale | 23 (5.0) | 29 (10.2) | 39 (16.7) | 47 (8.6) | |
PANSS total | 40 (5.8) | 52 (21.1) | 74 (33.9) | 88 (16.3) |