Table 1 Synaptic parameters for neuronal connectivity.
From: In silico hippocampal modeling for multi-target pharmacotherapy in schizophrenia
Presynaptic | Postsynaptic | Receptor | Ï„1 (ms) | Ï„2 (ms) | Conductance (nS) | Convergence |
|---|---|---|---|---|---|---|
Pyramidal | Pyramidal | AMPA | 0.05 | 5.3 | 0.02 | 25 |
Pyramidal | Pyramidal | NMDA | 15 | 150 | 0.004 | 25 |
Pyramidal | Basket | AMPA | 0.05 | 5.3 | 0.36 | 100 |
Pyramidal | Basket | NMDA | 15 | 150 | 1.38 | 100 |
Pyramidal | OLM | AMPA | 0.05 | 5.3 | 0.36 | 10 |
Pyramidal | OLM | NMDA | 15 | 150 | 0.7 | 10 |
Basket | Pyramidal | GABAA | 0.07 | 9.1 | 0.72 | 50 |
Basket | Basket | GABAA | 0.07 | 9.1 | 4.5 | 60 |
Basket | OLM | GABAA | 0.07 | 9.1 | 0.023 | 1 |
OLM | Pyramidal | GABAA | 0.2 | 20 | 72 | 20 |
