Fig. 1: Pipeline for computing a person-based similarity index.
From: Personalized estimates of morphometric similarity in bipolar disorder and schizophrenia
The Person-Based Similarity Index (PBSI) quantifies the similarity of an individual’s morphometric profile to those of all other individuals in the same group. a Creation of a structural profile (P) using regional measures (R) (e.g., cortical thickness or subcortical volumes) for each individual i. b Computation of Spearman’s correlation ρ between each pair of individual profiles. c For each individual i, the person-based similarity index (PBSI) is computed as the average of all pairwise correlations between individual i and all other individuals within the same group.
