Table 3 Linear regression models with ACC Glx as the independent variable of interest, predicting cognitive performance.

From: Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study

 

Unadjusted

Model 1

Model 2

β

95% CI

P

β

95% CI

P

β

95% CI

P

Dependent variable: cognitive outcome

 Verbal memory

3.19

0.83, 5.56

0.009*

3.40

0.88, 5.91

0.009*

3.38

0.84, 5.91

0.01*

 Verbal fluency

0.58

−1.44, 2.59

0.57

0.84

−1.30, 2.99

0.44

0.77

−1.38, 2.92

0.48

 Working memory

1.04

0.10, 1.97

0.03*

0.69

−0.30, 1.68

0.17

0.69

−0.30, 1.69

0.17

 Attention & information processing speed

2.16

−0.27, 4.59

0.08

1.58

−1.01, 4.17

0.23

1.48

−1.11, 4.07

0.26

 Motor speed

2.80

−0.41, 6.03

0.09

3.10

−0.19, 6.39

0.06

3.05

−0.27, 6.37

0.07

 Executive function

1.03

0.15, 1.90

0.02*

0.90

−0.04, 1.84

0.06

0.92

−0.03, 1.87

0.06

 BACS-t

2.86

−0.07, 5.80

0.06

2.98

−0.20, 6.16

0.07

2.88

−0.33, 6.08

0.08

 BACS-z

0.26

−0.03, 0.56

0.08

0.29

−0.03, 0.61

0.08

0.28

−0.05, 0.60

0.09

  1. *P < 0.05.
  2. Model 1 adjusts for age and sex. Model 2 adjusts for age, sex and CPZE dose.
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