Fig. 2: Expression of sensory (low-level) and volatility (high-level) precision-weighted prediction errors (pwPEs) in clinically high-risk group. | Schizophrenia

Fig. 2: Expression of sensory (low-level) and volatility (high-level) precision-weighted prediction errors (pwPEs) in clinically high-risk group.

From: Atypical prediction error learning is associated with prodromal symptoms in individuals at clinical high risk for psychosis

Fig. 2

A Maximum intensity projections of the significant clusters over left to right and anterior to posterior scalp locations (left) of the F-statistic for low-level pwPEs (ε2). Significant cluster-level effects (p < 0.05, whole-volume family wise error (FWE) corrected at the cluster level with a cluster-defining threshold of p < 0.001) are shown using a jet colour-map and significant peak-level effects (p < 0.05, whole-volume FWE-corrected at the peak level) are marked by black contours. Coloured area highlights f-values that exceed the cluster-defining threshold of p < 0.001, uncorrected. Time windows of significant cluster-level effects (earliest to latest significant timepoints) are illustrated by yellow bars on the right of the F-map. The scalp maps (right) show the peak effect of the given cluster with an F-map at the indicated peristimulus time, across a 2D representation of the sensor layout. Note that the global peak effect is not always expressed at a specific channel location. Significant correlations with the low-level pwPE ε2 peaked at 186 ms in frontocentral channels (sensor F3 and FC1). B Event-related potential waveforms averaged across the 15% highest and the 15% lowest pwPE values at electrodes within the significant clusters. C, D Significant correlations with the high-level pwPE ε3 peaked at 180 ms and 264 ms in central channels (sensor Cz), and at 400 ms in frontocentral channels (sensor FC2).

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