Table 5 Multiple linear regression analysis of factors influencing PANSS-N sub-scores in patients.

From: The role of ferroptosis and oxidative stress in cognitive deficits among chronic schizophrenia patients: a multicenter investigation

Variable

b

SE b

Ī²

t

P

95% CI

ACSL4 (ng/mL)

0.27

0.10

0.18

2.71

0.007

[0.072, 0.460]

GPX4 (ng/mL)

āˆ’0.37

0.13

āˆ’0.19

āˆ’2.76

0.006

[āˆ’0.629, āˆ’0.104]

GSH (g/L)

āˆ’0.26

0.19

āˆ’0.10

āˆ’1.39

0.167

[āˆ’0.629, 0.110]

FE (ng/mL)

3.55

1.23

0.19

2.88

0.004

[1.123, 5.982]

TF (mg/mL)

āˆ’0.69

0.38

āˆ’0.12

āˆ’1.80

0.073

[āˆ’1.451, 0.065]

SIRT1 (ng/mL)

āˆ’0.21

0.70

āˆ’0.02

āˆ’0.30

0.762

[āˆ’1.594, 1.169]

MDA (nmol/mL)

0.10

0.18

0.04

0.54

0.591

[āˆ’0.259, 0.454]

  1. PANSS-N positive and negative syndrome scale-negative symptoms, ACSL4 acyl-CoA synthase long-chain family member 4, GPX4 glutathione peroxidase 4, GSH glutathione, FE ferritin, TF transferrin, SIRT1 Sirtuin 1, MDA malondialdehyde.
  2. b Means unstandardized regression coefficient; B means standardized regression coefficient.
  3. R2ā€‰=ā€‰0.223, adjusted R2ā€‰=ā€‰0.195, Fā€‰=ā€‰8.045, Pā€‰<ā€‰0.001.
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