Table 6 Multiple linear regression analysis of factors influencing total MoCA scores in patients.

From: The role of ferroptosis and oxidative stress in cognitive deficits among chronic schizophrenia patients: a multicenter investigation

Variable

b

SE b

β

t

P

95%CI

Age (years)

0.00

0.02

0.00

āˆ’0.07

0.944

[āˆ’0.036, 0.034]

ACSL4 (ng/mL)

āˆ’0.12

0.04

āˆ’0.18

āˆ’2.75

0.007

[āˆ’0.204, āˆ’0.034]

GPX4 (ng/mL)

0.16

0.06

0.19

2.81

0.005

[0.049, 0.280]

GSH (g/L)

0.14

0.08

0.11

1.72

0.088

[āˆ’0.021, 0.303]

FE (ng/mL)

āˆ’1.39

0.55

āˆ’0.16

āˆ’2.55

0.012

[āˆ’2.464, āˆ’0.313]

TF (mg/mL)

0.30

0.17

0.12

1.77

0.078

[āˆ’0.034, 0.636]

SIRT1 (ng/mL)

0.14

0.31

0.03

0.47

0.641

[āˆ’0.466, 0.755]

SOD (U/mL)

āˆ’0.04

0.02

āˆ’0.13

āˆ’1.96

0.052

[āˆ’0.088, 0.000]

MDA (nmol/mL)

āˆ’0.07

0.08

āˆ’0.06

āˆ’0.88

0.378

[āˆ’0.227, 0.087]

  1. MoCA Montreal cognitive assessment, ACSL4 acyl-CoA synthase long-chain family member 4, GPX4 glutathione peroxidase 4, GSH glutathione, FE ferritin, TF transferrin, SIRT1 Sirtuin 1, SOD superoxide dismutase, MDA malondialdehyde.
  2. b Means unstandardized regression coefficient; B means standardized regression coefficient.
  3. R2 = 0.276, adjusted R2 = 0.243, F = 8.234, P < 0.001.